Placenta-specific1 (PLAC1) is a potential target for antibody-drug conjugate-based prostate cancer immunotherapy

Our recent findings strongly support the idea of PLAC1 being as a potential immunotherapeutic target in prostate cancer (PCa). Here, we have generated and evaluated an anti-placenta-specific1 (PLAC1)-based antibody drug conjugate (ADC) for targeted immunotherapy of PCa. Prostate cancer cells express...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nejadmoghaddam, Mohammad-Reza, Zarnani, Amir-Hassan, Ghahremanzadeh, Ramin, Ghods, Roya, Mahmoudian, Jafar, Yousefi, Maryam, Nazari, Mahboobeh, Ghahremani, Mohammad Hossein, Abolhasani, Maryam, Anissian, Ali, Mahmoudi, Morteza, Dinarvand, Rassoul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645454/
https://ncbi.nlm.nih.gov/pubmed/29042604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13682-9
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