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Optimization of Sample Preparation and Instrumental Parameters for the Rapid Analysis of Drugs of Abuse in Hair samples by MALDI-MS/MS Imaging

Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) has been employed to rapidly screen longitudinally sectioned drug user hair samples for cocaine and its metabolites using continuous raster imaging. Optimization of the spatial resolution and raster speed were performe...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Flinders, Bryn, Beasley, Emma, Verlaan, Ricky M., Cuypers, Eva, Francese, Simona, Bassindale, Tom, Clench, Malcolm R., Heeren, Ron M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645433/
https://ncbi.nlm.nih.gov/pubmed/28801836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1766-0
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