GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity

Maturation of human natural killer cells (NK cells) as defined by accumulation of cell surface expression of CD57 is associated with increased cytotoxic character and TNF and IFN-γ production upon target cell recognition. Notably, multiple studies point to a unique role for CD57(+) NK cells in cance...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Cichocki, Frank, Valamehr, Bahram, Bjordahl, Ryan, Zhang, Bin, Rezner, Betsy, Rogers, Paul, Gaidarova, Svetlana, Moreno, Stacey, Tuininga, Katie, Dougherty, Philip, McCullar, Valarie, Howard, Peter, Sarhan, Dhifaf, Taras, Emily, Schlums, Heinrich, Abbot, Stewart, Shoemaker, Daniel, Bryceson, Yenan T., Blazar, Bruce R., Wolchko, Scott, Cooley, Sarah, Miller, Jeffrey S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645243/
https://ncbi.nlm.nih.gov/pubmed/28790065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0799
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