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Contribution of Kupffer cells to liposome accumulation in the liver

The liver is a major barrier for site-specific delivery of systemically injected nanoparticles, as up to 90% of the dose is usually captured by this organ. Kupffer cells are thought to be the main cellular component responsible for nanoparticle accumulation in the liver. These resident macrophages f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Colloids Surf B Biointerfaces
Hauptverfasser: Samuelsson, Emma, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro, Wolfram, Joy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645238/
https://ncbi.nlm.nih.gov/pubmed/28719856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2017.07.014
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