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CHEMOPREVENTIVE EFFICACY OF CURCUMIN LOADED PLGA MICROPARTICLES IN A TRANSGENIC MOUSE MODEL OF HER-2 POSITIVE BREAST CANCER

Curcumin has shown promising inhibitory activity against HER-2 positive tumor cells in vitro but suffers from poor oral bioavailability in vivo. Our lab has previously developed a polymeric microparticle formulation for sustained delivery of curcumin for chemoprevention. The goal of this study was t...

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Bibliografiske detaljer
Udgivet i:Drug Deliv Transl Res
Main Authors: Grill, Alex E., Shahani, Komal, Koniar, Brenda, Panyam, Jayanth
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645218/
https://ncbi.nlm.nih.gov/pubmed/28417445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0377-4
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