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A mutation-resistant deoxyribozyme OR gate for highly selective detection of viral nucleic acids()
Highly selective probes hybridize only to fully complementary DNA or RNA sequences and, therefore, often fail to recognize mutated viral genomes. Here we designed a probe that possesses two seemingly incompatible properties: it tolerates some point mutations in genome, while it remains selective tow...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5645154/ https://ncbi.nlm.nih.gov/pubmed/28900642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc05576e |
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