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A mutation-resistant deoxyribozyme OR gate for highly selective detection of viral nucleic acids()

Highly selective probes hybridize only to fully complementary DNA or RNA sequences and, therefore, often fail to recognize mutated viral genomes. Here we designed a probe that possesses two seemingly incompatible properties: it tolerates some point mutations in genome, while it remains selective tow...

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Dades bibliogràfiques
Publicat a:Chem Commun (Camb)
Autors principals: Kamar, Ola, Sun, Sin-Cih, Lin, Chieh-Hua, Chung, Wan-Yu, Lee, Min-Shi, Liao, Yu-Chieh, Kolpashchikov, Dmitry M., Chuang, Min-Chieh
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645154/
https://ncbi.nlm.nih.gov/pubmed/28900642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc05576e
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