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Dexamethasone-mediated inhibition of Glioblastoma neurosphere dispersal in an ex vivo organotypic neural assay

Glioblastoma is highly aggressive. Early dispersal of the primary tumor renders localized therapy ineffective. Recurrence always occurs and leads to patient death. Prior studies have shown that dispersal of Glioblastoma can be significantly reduced by Dexamethasone (Dex), a drug currently used to co...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Meleis, Ahmed M., Mahtabfar, Aria, Danish, Shabbar, Foty, Ramsey A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645119/
https://ncbi.nlm.nih.gov/pubmed/29040322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186483
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