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EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity

Enteropathogenic Escherichia coli (EPEC) uses a type three secretion system to inject effector proteins into host intestinal epithelial cells causing diarrhea. EPEC infection redistributes basolateral proteins β1-integrin and Na(+)/K(+) ATPase to the apical membrane of host cells. The Crumbs (Crb) p...

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Bibliografiske detaljer
Udgivet i:Cell Microbiol
Main Authors: Tapia, Rocio, Kralicek, Sarah E., Hecht, Gail A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645036/
https://ncbi.nlm.nih.gov/pubmed/28618099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12757
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