Intraoperative ketamine does not affect postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial

BACKGROUND: Delirium and pain are common and serious postoperative complications. Subanaesthetic ketamine is often administered intraoperatively for postoperative analgesia and to spare postoperative opioids. Some evidence also suggests that ketamine prevents delirium. The primary purpose of this tr...

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Vydáno v:Lancet
Hlavní autoři: Avidan, Michael S., Maybrier, Hannah R., Abdallah, Arbi Ben, Jacobsohn, Eric, Vlisides, Phillip E., Pryor, Kane O., Veselis, Robert A., Grocott, Hillary P., Emmert, Daniel A., Rogers, Emma M., Downey, Robert J., Yulico, Heidi, Noh, Gyu-Jeong, Lee, Yonghun, Waszynski, Christine M., Arya, Virendra K., Pagel, Paul S., Hudetz, Judith A., Muench, Maxwell R., Fritz, Bradley A., Waberski, Witold, Inouye, Sharon K., Mashour, George A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644286/
https://ncbi.nlm.nih.gov/pubmed/28576285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)31467-8
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