Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

BACKGROUND: Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only Th1 but...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Prajeeth, Chittappen K., Kronisch, Julius, Khorooshi, Reza, Knier, Benjamin, Toft-Hansen, Henrik, Gudi, Viktoria, Floess, Stefan, Huehn, Jochen, Owens, Trevor, Korn, Thomas, Stangel, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644084/
https://ncbi.nlm.nih.gov/pubmed/29037246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0978-3
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