The wide spectrum of POT1 gene variants correlates with multiple cancer types

The POT1 protein binds and protects telomeres. Germline variants in the POT1 gene have recently been shown to be associated with risk of developing tumors in different tissues such as familial chronic lymphocytic leukemia, colorectal, glioma and melanoma tumors. Recently, we uncovered a variant in t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Eur J Hum Genet
Auteurs principaux: Calvete, Oriol, Garcia-Pavia, Pablo, Domínguez, Fernando, Bougeard, Gaelle, Kunze, Kristin, Braeuninger, Andreas, Teule, Alex, Lasa, Adriana, Ramón y Cajal, Teresa, Llort, Gemma, Fernández, Victoria, Lázaro, Conxi, Urioste, Miguel, Benitez, Javier
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Short Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643968/
https://ncbi.nlm.nih.gov/pubmed/28853721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.134
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