The wide spectrum of POT1 gene variants correlates with multiple cancer types

The POT1 protein binds and protects telomeres. Germline variants in the POT1 gene have recently been shown to be associated with risk of developing tumors in different tissues such as familial chronic lymphocytic leukemia, colorectal, glioma and melanoma tumors. Recently, we uncovered a variant in t...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Calvete, Oriol, Garcia-Pavia, Pablo, Domínguez, Fernando, Bougeard, Gaelle, Kunze, Kristin, Braeuninger, Andreas, Teule, Alex, Lasa, Adriana, Ramón y Cajal, Teresa, Llort, Gemma, Fernández, Victoria, Lázaro, Conxi, Urioste, Miguel, Benitez, Javier
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643968/
https://ncbi.nlm.nih.gov/pubmed/28853721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.134
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