A facile access and evaluation of some novel thiazole and 1,3,4-thiadiazole derivatives incorporating thiazole moiety as potent anticancer agents

BACKGROUND: Many heterocyclic compounds containing thiazole or 1,3,4-thiadiazole ring in their skeletons have been reported to possess various pharmacological activities especially anticancer activities. RESULTS: 4-Methyl-2-phenylthiazole-5-carbohydrazide (2) was used as a synthon to prepare 2-(4-me...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Cent J
Hauptverfasser: Gomha, Sobhi M., Abdelaziz, Mohamad R., Kheder, Nabila A., Abdel-aziz, Hassan M., Alterary, Seham, Mabkhot, Yahia N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643583/
https://ncbi.nlm.nih.gov/pubmed/29086869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0335-8
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