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Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction

Vascular endothelial growth factor (VEGF) plays important roles in improvement of cardiac function following myocardial infarction (MI). However, the lack of a steerable delivery system of VEGF targeting the infarcted myocardium reduces the therapeutic efficacy and safety. Here, we constructed a ser...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xia, Jing-Bo, Wu, Hai-Yan, Lai, Bing-Lin, Zheng, Li, Zhou, Deng-Cheng, Chang, Zao-Shang, Mao, Cheng-Zhou, Liu, Guang-Hui, Park, Kyu-Sang, Zhao, Hui, Kim, Soo-Ki, Song, Guo-Hua, Cai, Dong-Qing, Qi, Xu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643404/
https://ncbi.nlm.nih.gov/pubmed/29038511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13547-1
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