Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation

PURPOSE: Comparison of the dissociation kinetics of rapid-acting insulins lispro, aspart, glulisine and human insulin under physiologically relevant conditions. METHODS: Dissociation kinetics after dilution were monitored directly in terms of the average molecular mass using combined static and dyna...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Gast, Klaus, Schüler, Anja, Wolff, Martin, Thalhammer, Anja, Berchtold, Harald, Nagel, Norbert, Lenherr, Gudrun, Hauck, Gerrit, Seckler, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643355/
https://ncbi.nlm.nih.gov/pubmed/28762200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2233-0
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