Development of an athyroid mouse model using (131)I ablation after preparation with a low-iodine diet

We optimized the protocol for thyroid ablation in living mice using radioactive iodine (RAI) and a low-iodine diet (LID). To examine the effect of LID on thyroid ablation, mice were randomly divided into 4 groups: Vehicle, (131)I 2.775 MBq, (131)I 5.55 MBq, and LID + (131)I 2.775 MBq. The LID group...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oh, Ji Min, Lee, Ho Won, Kalimuthu, Senthilkumar, Gangadaran, Prakash, Baek, Se Hwan, Han, Man-Hoon, Hong, Chae Moon, Jeong, Shin Young, Lee, Sang-Woo, Lee, Jaetae, Ahn, Byeong-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643325/
https://ncbi.nlm.nih.gov/pubmed/29038462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13772-8
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