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Prokineticin receptor-1-dependent paracrine and autocrine pathways control cardiac tcf21(+) fibroblast progenitor cell transformation into adipocytes and vascular cells

Cardiac fat tissue volume and vascular dysfunction are strongly associated, accounting for overall body mass. Despite its pathophysiological significance, the origin and autocrine/paracrine pathways that regulate cardiac fat tissue and vascular network formation are unclear. We hypothesize that adip...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qureshi, Rehana, Kindo, Michel, Arora, Himanshu, Boulberdaa, Mounia, Steenman, Marja, Nebigil, Canan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643307/
https://ncbi.nlm.nih.gov/pubmed/29038558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13198-2
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