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An efficient study design to test parent-of-origin effects in family trios

Increasing evidence has shown that genes may cause prenatal, neonatal, and pediatric diseases depending on their parental origins. Statistical models that incorporate parent-of-origin effects (POEs) can improve the power of detecting disease-associated genes and help explain the missing heritability...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Yu, Xiaobo, Chen, Gao, Feng, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643247/
https://ncbi.nlm.nih.gov/pubmed/28726280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22060
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