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Impact of intrapatient variability (IPV) in tacrolimus trough levels on long-term renal transplant function: multicentre collaborative retrospective cohort study protocol

INTRODUCTION: High intrapatient variability (IPV) in tacrolimus trough levels has been shown to be associated with higher rates of renal transplant failure. There is no consensus on what level of IPV constitutes a risk of graft loss. The establishment of such a threshold could help to guide clinicia...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Goldsmith, Petra M, Bottomley, Matthew J, Okechukwu, Okidi, Ross, Victoria C, Ghita, Ryan, Wandless, David, Falconer, Stuart J, Papachristos, Stavros, Nash, Philip, Androshchuk, Vitaliy, Clancy, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642769/
https://ncbi.nlm.nih.gov/pubmed/28756385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-016144
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