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Rewiring a Rab regulatory network reveals a possible inhibitory role for the vesicle tether, Uso1
Ypt1 and Sec4 are essential Rab GTPases that control the early and late stages of the yeast secretory pathway, respectively. A chimera consisting of Ypt1 with the switch I domain of Sec4, Ypt1-SW1(Sec4), is efficiently activated in vitro by the Sec4 exchange factor, Sec2. This should lead to its ect...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642711/ https://ncbi.nlm.nih.gov/pubmed/28973856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708394114 |
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