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Kinesin rotates unidirectionally and generates torque while walking on microtubules

Cytoskeletal motors drive many essential cellular processes. For example, kinesin-1 transports cargo in a step-wise manner along microtubules. To resolve rotations during stepping, we used optical tweezers combined with an optical microprotractor and torsion balance using highly birefringent microsp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ramaiya, Avin, Roy, Basudev, Bugiel, Michael, Schäffer, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642696/
https://ncbi.nlm.nih.gov/pubmed/28973906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706985114
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