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RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye

Carotenoids are plant-derived pigment molecules that vertebrates cannot synthesize de novo that protect the fovea of the primate retina from oxidative stress and light damage. meso-Zeaxanthin is an ocular-specific carotenoid for which there are no common dietary sources. It is one of the three major...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Shyam, Rajalekshmy, Gorusupudi, Aruna, Nelson, Kelly, Horvath, Martin P., Bernstein, Paul S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642693/
https://ncbi.nlm.nih.gov/pubmed/28874556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706332114
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