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Downregulation of lncRNA X Inactive Specific Transcript (XIST) Suppresses Cell Proliferation and Enhances Radiosensitivity by Upregulating mir-29c in Nasopharyngeal Carcinoma Cells

BACKGROUND: LncRNA X inactive specific transcript (XIST) was reported to function as an oncogene in nasopharyngeal carcinoma cells (NPC) by sponging miR-34a-5p. However, the role of XIST in modulating the radiosensitivity of NPC cells and its mechanism still remain undefined. MATERIAL/METHODS: The e...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Han, Qian, Li, Liang, Liang, Hengpo, Li, Yaqiong, Xie, Jiacun, Wang, Zhibin
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642646/
https://ncbi.nlm.nih.gov/pubmed/28985197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905370
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