Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

Epoxyeicosatrienoic acid (EET) production via cytochrome P450 (CYP) epoxygenases closely correlates with the progression of breast cancer. However, its role in the development of chemoresistant breast cancers has yet to be elucidated. Here, we found that CYP3A4 expression and its epoxy-product, 11,1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Thuy Phuong, Nguyen Thi, Kim, Ji Won, Kim, Jung-Ae, Jeon, Jang Su, Lee, Ji-Yoon, Xu, Wen Jun, Yang, Jin Won, Kim, Sang Kyum, Kang, Keon Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642617/
https://ncbi.nlm.nih.gov/pubmed/29050342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20329
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