Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

Epoxyeicosatrienoic acid (EET) production via cytochrome P450 (CYP) epoxygenases closely correlates with the progression of breast cancer. However, its role in the development of chemoresistant breast cancers has yet to be elucidated. Here, we found that CYP3A4 expression and its epoxy-product, 11,1...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Thuy Phuong, Nguyen Thi, Kim, Ji Won, Kim, Jung-Ae, Jeon, Jang Su, Lee, Ji-Yoon, Xu, Wen Jun, Yang, Jin Won, Kim, Sang Kyum, Kang, Keon Wook
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642617/
https://ncbi.nlm.nih.gov/pubmed/29050342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20329
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