Inhibition of proliferation and invasion in 2D and 3D models by 2-methoxyestradiol in human melanoma cells

Despite the recent advances in the clinical management of melanoma, there remains a need for new pharmacological approaches to treat this cancer. 2-methoxyestradiol (2ME) is a metabolite of estrogen that has shown anti-tumor effects in many cancer types. In this study we show that 2ME treatment lead...

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Udgivet i:Pharmacol Res
Main Authors: Massaro, R.R, Faião-Flores, F, Rebecca, V.W, Sandri, S, Alves-Fernandes, D.K, Pennacchi, P.C, Smalley, K.S.M., Maria-Engler, S.S
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642284/
https://ncbi.nlm.nih.gov/pubmed/28212889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.02.013
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