Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN

The human C-type lectin DC-SIGN (CD209) is a significant receptor on the surface of dendritic cells (DCs) – crucial components of host defense that bridge the innate and adaptive immune systems. A range of linear glycopolymers, constructed via controlled radical polymerization techniques have been s...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Mitchell, Daniel A., Zhang, Qiang, Voorhaar, Lenny, Haddleton, David M., Herath, Shan, Gleinich, Anne S., Randeva, Harpal S., Crispin, Max, Lehnert, Hendrik, Wallis, Russell, Patterson, Steven, Becer, C. Remzi
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642150/
https://ncbi.nlm.nih.gov/pubmed/29147524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01515a
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