Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN

The human C-type lectin DC-SIGN (CD209) is a significant receptor on the surface of dendritic cells (DCs) – crucial components of host defense that bridge the innate and adaptive immune systems. A range of linear glycopolymers, constructed via controlled radical polymerization techniques have been s...

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Dettagli Bibliografici
Pubblicato in:Chem Sci
Autori principali: Mitchell, Daniel A., Zhang, Qiang, Voorhaar, Lenny, Haddleton, David M., Herath, Shan, Gleinich, Anne S., Randeva, Harpal S., Crispin, Max, Lehnert, Hendrik, Wallis, Russell, Patterson, Steven, Becer, C. Remzi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642150/
https://ncbi.nlm.nih.gov/pubmed/29147524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01515a
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