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Corona Discharge Suppression in Negative Ion Mode Nanoelectrospray Ionization via Trifluoroethanol Addition
Negative ion mode nanoelectrospray ionization (nESI) is often utilized to analyze acidic compounds, from small molecules to proteins, with mass spectrometry (MS). Under high aqueous solvent conditions corona discharge is commonly observed at emitter tips, resulting in low ion abundances and reduced...
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| Publicado no: | Anal Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642034/ https://ncbi.nlm.nih.gov/pubmed/28841300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01225 |
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