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Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages

Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to defective autophagy, causing continued system...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shrestha, Chandra L., Assani, Kaivon D., Rinehardt, Hannah, Albastroiu, Florentina, Zhang, Shuzhong, Shell, Richard, Amer, Amal O., Schlesinger, Larry S., Kopp, Benjamin T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642023/
https://ncbi.nlm.nih.gov/pubmed/28982193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186169
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