AB074. Genetic variation in CYP2U1, CYP4A11 and CYP4F2 involved in the biosynthesis of hydroxyeicosatetraenoic acids and susceptibility to hypertension and atherosclerosis of various locations

BACKGROUND: 20-hydroxyeicosatetraenoic acids (20-HETE), products of arachidonic acid metabolism, possess a wide spectrum of important functions in the cardiovascular system and thereby may contribute to the development of many cardiovascular diseases (CVD). CYP2U1, CYP4A11 and CYP4F2 are important e...

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Bibliographic Details
Published in:Ann Transl Med
Main Authors: Polonikov, Alexey, Sirotina, Svetlana, Ponomarenko, Irina, Shvetsov, Yaroslav, Bykanova, Marina, Bocharova, Anna, Vagaytseva, Kseniya, Stepanov, Vadim, Solodilova, Maria
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2017
Subjects:
Molecular Genetics, Genomics, Mechanisms of Diseases
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641768/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.s074
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