AB066. The association between GATA1 mutations in Down syndrome newborns and transient abnormal myelopoiesis

BACKGROUND: Children with Down syndrome (DS) are 500 times more likely to develop acute myeloid leukemia (AML-DS), compared to children without DS. One of the potential risk factors for AML-DS is a history of transient abnormal myelopoiesis (TAM) in the newborn period, which is found in approximatel...

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Опубликовано в: :Ann Transl Med
Главные авторы: Chukua, Kanokporn, Netsawang, Chayanont, Padungthai, Kittipoom, Khetkham, Thanitchet, Surapolchai, Pacharapan, Rojnueangnit, Kitiwan
Формат: Artigo
Язык:Inglês
Опубликовано: AME Publishing Company 2017
Предметы:
Molecular Genetics, Genomics, Mechanisms of Diseases
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641727/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.s066
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