A Standardized Wedelia chinensis Extract Overcomes the Feedback Activation of HER2/3 Signaling upon Androgen-Ablation in Prostate Cancer

Crosstalk between the androgen receptor (AR) and other signaling pathways in prostate cancer (PCa) severely affects the therapeutic outcome of hormonal therapy. Although anti-androgen therapy prolongs overall survival in PCa patients, resistance rapidly develops and is often associated with increase...

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Vydáno v:Front Pharmacol
Hlavní autoři: Tsai, Chin-Hsien, Tzeng, Sheue-Fen, Hsieh, Shih-Chuan, Tsai, Chia-Jui, Yang, Yu-Chih, Tsai, Mong-Hsun, Hsiao, Pei-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641394/
https://ncbi.nlm.nih.gov/pubmed/29066975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00721
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