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Connexin43- and Pannexin-Based Channels in Neuroinflammation and Cerebral Neuropathies

Connexins (Cx) are largely represented in the central nervous system (CNS) with 11 Cx isoforms forming intercellular channels. Moreover, in the CNS, Cx43 can form hemichannels (HCs) at non-junctional membrane as does the related channel-forming Pannexin1 (Panx1) and Panx2. Opening of Panx1 channels...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Sarrouilhe, Denis, Dejean, Catherine, Mesnil, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641369/
https://ncbi.nlm.nih.gov/pubmed/29066951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00320
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