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Germline mutations in pancreatic cancer and potential new therapeutic options

Due to short-lived treatment responses in unresectable disease, pancreatic ductal adenocarcinoma (PDAC) continues to be one of the deadliest cancers. There is availability of new information about germline and sporadic mutations in the deoxyribonucleic acid (DNA) damage repair pathway in PDAC in rec...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pihlak, Rille, Valle, Juan W., McNamara, Mairéad G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641209/
https://ncbi.nlm.nih.gov/pubmed/29069866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17291
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