Induction of GD3/α1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cells

The disialic acid-containing glycosphingolipid GD3 recruited membrane transglutaminase 2 (TG2) as a signaling molecule for erythroid differentiation in human chronic myelogenous leukemia (CML) K562 cells. The α1-adrenergic receptor (α1-AR)/TG2-mediated signaling pathway regulated GD3 functions, incl...

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Publicado en:Oncotarget
Main Authors: Ha, Sun-Hyung, Kang, Sung-Koo, Choi, Hyunju, Kwak, Choong-Hwan, Abekura, Fukushi, Park, Jun-Young, Kwon, Kyung-Min, Chang, Hyeun-Wook, Lee, Young-Choon, Ha, Ki-Tae, Hou, Bo Kyeng, Chung, Tae-Wook, Kim, Cheorl-Ho
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641123/
https://ncbi.nlm.nih.gov/pubmed/29069780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20080
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