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Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth
The pathogenic role of the PHOX2B gene in neuroblastoma is indicated by heterozygous mutations in neuroblastoma patients and by gene overexpression in both neuroblastoma cell lines and tumor samples. PHOX2B encodes a transcription factor which is crucial for the correct development and differentiati...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641117/ https://ncbi.nlm.nih.gov/pubmed/29069774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19922 |
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