Transcriptional factor OCT4 promotes esophageal cancer metastasis by inducing epithelial-mesenchymal transition through VEGF-C/VEGFR-3 signaling pathway

The octamer-binding transcription factor 4 (OCT4) can promote cancer proliferation and metastasis. Esophageal carcinoma (ECC) harbors different quantities of OCT4-positive cancer cells. These cells are highly malignant and prone to metastasis; however, the mechanism remains unknown. In this study, w...

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Vydáno v:Oncotarget
Hlavní autoři: Li, Chunguang, Zhu, Maoling, Lou, Xiaoli, Liu, Chunying, Chen, Hezhong, Lin, Xuejing, Ji, Weidan, Li, Zhigang, Su, Changqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641101/
https://ncbi.nlm.nih.gov/pubmed/29069758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18035
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