A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells

Prep1 is a homeodomain transcription factor belonging to the TALE protein family. Its overexpression affects glucose metabolism in several tissues. In particular, in skeletal muscle tissue the interaction of Prep1 with its cofactor p160 impairs GLUT4 expression and glucose uptake. In this study, we...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Cimmino, Ilaria, Lorenzo, Virginia, Fiory, Francesca, Doti, Nunzianna, Ricci, Serena, Cabaro, Serena, Liotti, Antonietta, Vitagliano, Luigi, Longo, Michele, Miele, Claudia, Formisano, Pietro, Beguinot, Francesco, Ruvo, Menotti, Oriente, Francesco
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641094/
https://ncbi.nlm.nih.gov/pubmed/29069751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18286
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