A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells

Prep1 is a homeodomain transcription factor belonging to the TALE protein family. Its overexpression affects glucose metabolism in several tissues. In particular, in skeletal muscle tissue the interaction of Prep1 with its cofactor p160 impairs GLUT4 expression and glucose uptake. In this study, we...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cimmino, Ilaria, Lorenzo, Virginia, Fiory, Francesca, Doti, Nunzianna, Ricci, Serena, Cabaro, Serena, Liotti, Antonietta, Vitagliano, Luigi, Longo, Michele, Miele, Claudia, Formisano, Pietro, Beguinot, Francesco, Ruvo, Menotti, Oriente, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641094/
https://ncbi.nlm.nih.gov/pubmed/29069751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18286
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