Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

Pediatric high grade glioma (pHGGs), including sus-tentorial and diffuse intrinsic pontine gliomas, are known to have a very dismal prognosis. For instance, even an increased knowledge on molecular biology driving this brain tumor entity, there is no treatment able to cure those patients. Therefore,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nguyen, Aurélia, Moussallieh, François Marie, Mackay, Alan, Cicek, A. Ercument, Coca, Andres, Chenard, Marie Pierre, Weingertner, Noelle, Lhermitte, Benoit, Letouzé, Eric, Guérin, Eric, Pencreach, Erwan, Jannier, Sarah, Guenot, Dominique, Namer, Izzie Jacques, Jones, Chris, Entz-Werlé, Natacha
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641075/
https://ncbi.nlm.nih.gov/pubmed/29069732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16500
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