Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer

Increased AR activity has been shown to be preserved in spatially distinct metastatic tumors from the same patient suggesting the requirement for lineage-specific dependencies for metastatic castration resistant prostate cancer (mCRPC). Amplification of the AR gene is a common mechanism by which mCR...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Podolak, Jennifer, Eilers, Kristi, Newby, Timothy, Slottke, Rachel, Tucker, Erin, Olson, Susan B., Lue, Hui-Wen, Youngren, Jack, Aggarwal, Rahul, Small, Eric J., Graff, Julie N., Alumkal, Joshi J., Beer, Tomasz M., Thomas, George V.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2017
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641061/
https://ncbi.nlm.nih.gov/pubmed/29069718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16169
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