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Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes

BACKGROUND: Cells are able to communicate and coordinate their function within tissues via secreted factors. Aberrant secretion by cancer cells can modulate this intercellular communication, in particular in highly organised tissues such as the liver. Hepatocytes, the major cell type of the liver, s...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Hartung, Niklas, Benary, Uwe, Wolf, Jana, Kofahl, Bente
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640931/
https://ncbi.nlm.nih.gov/pubmed/29029622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0470-9
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