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Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes

BACKGROUND: Cells are able to communicate and coordinate their function within tissues via secreted factors. Aberrant secretion by cancer cells can modulate this intercellular communication, in particular in highly organised tissues such as the liver. Hepatocytes, the major cell type of the liver, s...

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Pubblicato in:BMC Syst Biol
Autori principali: Hartung, Niklas, Benary, Uwe, Wolf, Jana, Kofahl, Bente
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640931/
https://ncbi.nlm.nih.gov/pubmed/29029622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0470-9
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