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Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon

A hallmark of human immunodeficiency virus type 1 (HIV-1) infection in vivo is chronic immune activation concomitant with type I interferon (IFN) production. Although type I IFN induces an antiviral state in many cell types, HIV-1 can replicate in vivo via mechanisms that have remained unclear. We h...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Akiyama, Hisashi, Ramirez, Nora-Guadalupe Pina, Gibson, Gregory, Kline, Christopher, Watkins, Simon, Ambrose, Zandrea, Gummuluru, Suryaram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640826/
https://ncbi.nlm.nih.gov/pubmed/28794041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00972-17
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