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An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA(A) Receptors

Inhibitory synaptic transmission requires the targeting and stabilization of GABA(A) receptors (GABA(A)Rs) at synapses. The mechanisms responsible remain poorly understood, and roles for transmembrane accessory proteins have not been established. Using molecular, imaging, and electrophysiological ap...

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Publicat a:Cell Rep
Autors principals: Davenport, Elizabeth C., Pendolino, Valentina, Kontou, Georgina, McGee, Thomas P., Sheehan, David F., López-Doménech, Guillermo, Farrant, Mark, Kittler, Josef T.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640807/
https://ncbi.nlm.nih.gov/pubmed/28978485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.025
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