Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes. Molecular mimicry hypothesizes that a sequence homology between foreign and self-pep...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Pahari, Susanta, Chatterjee, Deepyan, Negi, Shikha, Kaur, Jagdeep, Singh, Balvinder, Agrewala, Javed N.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640720/
https://ncbi.nlm.nih.gov/pubmed/29062305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01938
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