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Harmine, a Novel DNA Methyltransferase 1 Inhibitor in the Leukemia Cell Line

DNA methylation followed by tumor suppressor gene repression plays a critical role in the leukemia development. So, DNA methyl transferase inhibitors have great importance in treatment of theses malignancies. Harmine, A beta carboline alkaloid derivative of Peganum harmala, had shown anti- prolifera...

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Библиографические подробности
Опубликовано в: :Indian J Hematol Blood Transfus
Главные авторы: Oodi, Arezoo, Norouzi, Hamed, Amirizadeh, Naser, Nikougoftar, Mahin, Vafaie, Zahra
Формат: Artigo
Язык:Inglês
Опубликовано: Springer India 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640528/
https://ncbi.nlm.nih.gov/pubmed/29075061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12288-016-0770-z
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