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Midostaurin: a novel therapeutic agent for patients with FLT3-mutated acute myeloid leukemia and systemic mastocytosis

The development of FLT3-targeted inhibitors represents an important paradigm shift in the management of patients with highly aggressive fms-like tyrosine kinase 3-mutated (FLT3-mut) acute myeloid leukemia (AML). Midostaurin is an orally administered type III tyrosine kinase inhibitor which in additi...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Gallogly, Molly M., Lazarus, Hillard M., Cooper, Brenda W.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639976/
https://ncbi.nlm.nih.gov/pubmed/29051803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620717721459
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