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Genes Affecting Warfarin Response—Interactive or Additive?
Genotypes for cytochrome P450 (CYP) 2C9 and vitamin K epoxide reductase complex 1 (VKORC1) contribute significantly to the inter-patient variability in warfarin dose requirements. These genotypes in addition to clinical factors explain approximately 50% of the dose variability in Europeans, but less...
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| Pubblicato in: | J Clin Pharmacol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5639939/ https://ncbi.nlm.nih.gov/pubmed/25385663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.425 |
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