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Production of recombinant coagulation factors: Are humans the best host cells?

The main treatment option for Hemophilia A/B patients involves the administration of recombinant coagulation factors on-demand or in a prophylactic approach. Despite the safety and efficacy of this replacement therapy, the development of antibodies against the coagulation factor infused, which neutr...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Swiech, Kamilla, Picanço-Castro, Virgínia, Covas, Dimas Tadeu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639856/
https://ncbi.nlm.nih.gov/pubmed/28277160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2017.1279767
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