Exploration of 3,6-dihydroimidazo(4,5-d)pyrrolo(2,3-b)pyridin-2(1H)-one derivatives as JAK inhibitors using various in silico techniques

This study focuses on understanding the structural features of 3,6-dihydroimidazo(4,5-d)pyrrolo(2,3-b)pyridin-2(1H)-one (dpp) derivatives to computationally identify new JAK inhibiting compounds. For the purpose, a novel virtual screening strategy, with 2D and 3D-QSAR (CoMFA and CoMSIA), data mining...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:In Silico Pharmacol
Main Authors: Jisha, Radhakrishnan S., Aswathy, Lilly, Masand, Vijay H., Gajbhiye, Jayant M., Shibi, Indira G.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639824/
https://ncbi.nlm.nih.gov/pubmed/29085766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-017-0029-x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares