In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma

Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) could potentially provide unlimited HSCs for clinical transplantation, a curative treatment for numerous blood diseases. However, to date, bona fide HSC generation has been largely unsuccessful in vitro. We have previou...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tsukada, Masao, Ota, Yasunori, Wilkinson, Adam C., Becker, Hans J., Osato, Motomi, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639260/
https://ncbi.nlm.nih.gov/pubmed/28943250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.010
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