The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair

The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders. We therefore sought to model the inter-causality of these relationships under controlled laboratory conditions. We subjected humanized BDNF Val66Met (hBDNF(Val66Met)) transgenic mice to a history o...

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Sparad:
Bibliografiska uppgifter
I publikationen:Transl Psychiatry
Huvudupphovsmän: Notaras, M, Du, X, Gogos, J, van den Buuse, M, Hill, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639248/
https://ncbi.nlm.nih.gov/pubmed/28926000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2017.205
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