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Production and evaluation of parathyroid hormone receptor(1) ligands with intrinsic or assembled peroxidase domains
Parathyroid hormone (PTH) can be C-terminally extended without significant affinity loss for the PTH(1) receptor (PTHR(1)). We developed fusion protein ligands with enzymatic activity to probe PTHR(1)s at the cell surface. Two fusion proteins were generated by linking PTH to the N-terminus of either...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638942/ https://ncbi.nlm.nih.gov/pubmed/29026164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13548-0 |
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